Possible complications
- Significant bleeding which, depending on an ultrasound, may require an aspiration to eliminate intra-uterine decidual remains.
- Failure of the method and continuance of the pregnancy, which will require an aspiration of the uterine cavity (risk of malformation due to MISOPROSTOL).
- From the first consultation through to the uterus remaining completely clean, the “pills” technique may take two to several days and in a few cases may end in an aspiration, (1-3%).
DIFFERENCES BETWEEN SURGICAL AND MEDICAL TECHNIQUES:
- The aspiration technique is surgical, the gynaecologist intervenes, and from the administration of the anaesthesia and aspiration through to completion of the procedure lasts just some 5 to 8 minutes. Checking in the act that the uterus remains clean and empty through ultrasound scan.
- The MEDICAL ABORTION technique would be a more NATURAL method, (spontaneous abortion?), it is less invasive, no instruments are inserted into the vagina or uterine cavity, it gives the woman autonomy as it is she who fundamentally decides, intervenes and administers the medication, with the advice of the specialist, and with subsequent monitoring to ensure the uterus remains empty.
ATTACHED INFORMATION
FLASGO (Latin American Federation of Gynaecology and Obstetrics Societies), published these indications.
The following table compares the schemes based on evidence in France and at the FDA.
French schemes |
EU: FDA Scheme |
Evidence-based Scheme |
|
| Dose of MIFEPRISTONE | 600 mg (Day 1) | 600 mg (Day 1) | 200 mg (Day 1) |
| Dose of MISOPROSTOL | 400 µg, PO (alternative) 1mg gemeprost, PV) | 400 µg, PO | 400 µg, PO or 800 µg, PV |
| Gestational limit | < 49 days | < 49 days | < 63 days |
| Administration of MISOPROSTOL | Medical Consultancy / Clinic | Medical Consultancy / Clinic | Medical Consultancy / Clinic |
| Date on which MISOPROSTOL is administered | Day 2 or 3 | Day 3 | Day 2, 3 or 4 |
| Date of check-up | Day 10 to 14 | Day 14 | Day 4 to 14 |
| Number of clinical consultations | Three or more | Three or more | Two or more |
Regardless of the scheme chosen, there are various steps that should be followed to achieve an abortion with medication using MIFEPRISTONE-MISOPPROSTOL.
MIFEPRISTONE is recommended for the following indications:
1) For the medical interruption of a pregnancy:
- Up to a maximum of 63 days after the first day of your last menstrual period,
- In combination with another treatment (prostaglandin, a substance which increases the contraction of the uterus) which is taken 36 to 48 hours after taking MIFEPRISTONE.
2) To soften and dilate the neck of the uterus prior to the surgical interruption of a pregnancy during the first trimester.
3) As a treatment prior to the administration of prostaglandins for the interruption of pregnancy for medical reasons after the 3rd month of gestation.
4) To induce a birth in cases where the foetus has died in the uterus and when the use of other medical treatments (prostaglandins or oxytocinergic) is not possible.
